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The Next Era of Digital Health: A VC’s Perspective | Lee Shapiro

Digital health is entering a new era — one where informed consumers, smarter technology, and outcomes-based models reshape how care is delivered and funded. In this episode, Lee Shapiro of 7wire Ventures shares what he’s seeing across the industry, how employers are adapting, and why the next generation of startups will look different from those of the past.

Key Takeaways:

  • Today’s best digital health companies focus on consumer value, measurable outcomes, and ROI for the buyer.

  • Employers are shifting away from PMPM models to engagement-based or shared savings contracts.

  • CFOs now play a central role in benefits and digital health buying decisions.

  • Startups built by founders with lived experience are better positioned for long-term success.

00:00 – Intro + Guest welcome

01:25 – What is an informed, connected health consumer?

03:13 – Challenges facing employers + 7wire’s formula for ROI

06:42 – Where employers are seeing rising costs (surgical, pharma, mental health)

07:51 – Point solutions vs. platform fatigue

08:50 – Outcomes-based contracts replacing PMPM

09:25 – CFO’s growing role in benefits decisions

11:36 – Venture funding trends and valuation resets

13:47 – How 7wire uses AI in investing

15:33 – What really matters when investing: founders, relationships, mission

16:42 – Highlight: NOCD as a success story in severe mental illness care

17:30 – Wrap-up + final thoughts

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